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GAU 008-01-02 detects Complement factor D in human serum and plasma.
GAU 008-01-02 has been successfully used in ELISA and Western blot procedures. Use in Western blotting under non-reducing conditions. GAU 008-01 may be used as detection antibody in sandwich ELISA with GAU 010-04-02 as a capture antibody.
Complement factor D is a serine protease of the alternative pathway of complement activation. The protein is a single chain polypeptide with a molecular mass of 25 kDa. Factor D cleaves factor B bound to C3b, generating the alternative pathway C3 convertase C3bBb and releasing the Ba fragment.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adipsin; C3 convertase activator; Complement factor D; complement factor D (adipsin); complement factor D preproprotein; D component of complement (adipsin); EC 3.4.21.46; Properdin factor D
基因别名: ADIPSIN; ADN; CFD; DF; PFD
UniProt ID: (Human) P00746
Entrez Gene ID: (Human) 1675